CBD Oil In Canada – Best Sources And More

Ever thought how CBD and THC works? Thanks to its comparable structure to a compound produced by our bodies naturally, these natural chemicals are able to influence a specific network of our bodies known as the endocannabinoid system.

But what exactly is the endocannabinoid system and what are its roles?

The Mayo Clinic at mayoclinic.org loves CBD too.
Does Marijuana Damage Brain Cells? is an intersting read.

A Brief History of the Cannabis Discovery

Even before experts discovered the endocannabinoid system (ECS), cannabis had been a prominent medicinal herb since time immemorial. Historically, practitioners used it to treat a wide array of health issues such as pain, digestive complaints and convulsive disorders. Studies on the benefits of cannabis revealed a group of chemical compounds present in the plant called cannabinoids.

There are more than 80 various types of cannabinoids in different parts of cannabis, depending on the strain. However, the two most prominent cannabinoids are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). THC is psychoactive, which is responsible for the ‘high’ associated with cannabis use, while CBD is a non-psychoactive cannabinoid.

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In the 1940s, scientists were able to isolate cannabidiol (CBD). But it was in the mid-1960s that research on the psychotropic effect of cannabis led to the isolation of THC. The isolation of both CBD and THC ignited the interests of the medical community and further studies on the effect of these compounds on the human body has led to the discovery of what is known today as the Endocannabinoid System (ECS).

What is the Endocannabinoid System (ECS)?

The Endocannabinoid system is a group of specialized cell receptors of the human body and a particular set of molecules capable of binding to these receptors. These receptors and molecules work in a way similar to a lock and key.

Cannabinoid receptors come in two types – CB1 and CB2.

CB1 receptors are often found within the central nervous system, but are also present all over the body in lower concentrations. CB2 receptors are found in immune cells, in blood cell precursors and other bodily tissues.

CBD that actually works to relieve pain is in high demand.

Chemical molecules that attach to these receptors and activate the pathway are known as agonists. Those that bind yet prevent the pathway from being activated are called antagonists. THC can directly bind to CB1 and CB2 receptors to activate those pathways.

Cannabinoids are not naturally produced by the body so the existence of receptors CB1 and B2 that were triggered by these compounds wondered scientists and thought if the body produces its own chemical molecules that were similar to cannabinoids. Further research revealed a group of endogenous chemicals that are produced by the body to activate this pathway. They were called endocannabinoid (eCB). There are two types of endocannabinoid – anandamide, or bliss molecule and the 2-AG (2-Arachidonoyl glycerol).

Both Anandamide and 2-AG function in a similar way to THC – they bind to CB1 and CB2 receptors and activate those pathways. Apart from that, they also act as antagonist for a separate receptor, the vanilloid receptor, which works by regulating pain.
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What are the Functions of ECS?

Cannabinoid receptors can be found in different parts of the body, providing a broad range of functions. The different cannabinoid receptors locations just reveals the importance of endocannabinoids for everyday functions. Activating the ECS pathways has been found to influence the following processes:

• Regulation of temperature
• Immune system
• Fertility and reproduction
• Rest and Sleep
• Reward and pleasure
• Memory
• Appetite
• Digestion
• Hunger
• Mood
• Pain sensation
• Motor control

The Endocannabinoids Anandamide and 2-Ag tell the body to make these physiological processes above working. They help keep the optimal body known as the homeostasis. Disrupting the ECS can make any of these processes unbalanced. It is believed that dysregulation of the ECS contribute to a host of conditions, including irritable bowel syndrome (IBS) and fibromyalgia.

What is Clinical Endocannabinoid Deficiency?

Researchers believe that the main cause of many disorders and ailments, specifically those associated with inflammation and immune system, could be a disorder called clinical endocannabinoid deficiency. This is a speculated spectrum disorder that develop when the body’s endocannabinoid system isn’t working properly.

The theory suggests that sometimes, the body doesn’t produce enough eCBs or receptors for the endocannabinoid system to function well. Hence, the many physiological processes we discussed earlier could become unbalanced, causing diseases to arise.

What are Endocannabinoids Made Of?

Insufficient levels of endocannabinoids in the body can lead to a host of disorders and imbalances. Yet where do these endogenous molecules come from? The answer is simple – it’s from our diet.
The body produces endocannabinoids using fatty acid. An animal study has discovered a link between low Omega-3 diet and changes in mood due to improper endocannabinoid regulation.

Good news is, there are many dietary sources of Omega-3. Hemp seeds are a good source, but fatty fishes such as sardines, tuna and salmon contain a form of Omega-3 that can be utilized by the body quickly.

Targeting ECS for Therapeutic Management

Nearly 20 years after the discovery of endocannabinoids, all members of the ECS – the cannabinoid receptors and the endocannabinoids, including the metabolic enzymes, are now considered targets for the development of compounds that can modulate human physiological processes.

In fact, there are now drugs being used to modulate the endocannabinoid system. Examples are Dronabinol and Nabilone, cannabinoid receptor agonists, that are used to reduce chemotherapy-induced vomiting and Sativex (combination of CBD and THC) for treating multiple sclerosis spasticity. In the US, the drug Epidiolex (CBD) is under investigation for childhood seizures.

Currently, several diseases such as pain, inflammation, emesis, multiple sclerosis, epilepsy, anorexia, glaucoma, Huntington’s disease, Parkinson’s disease, Tourette’s Syndrome, schizophrenia, cancer, obesity and cardiovascular disorders could possibly be treated using treatments that could modulate the endocannabinoid system.

In order to successfully utilize the therapeutic potential of ECS, a deeper understanding on how the ECS works at the cellular level and their role as a protective substance can help in creating innovative cannabinoid-based therapies for a vast array of diseases and disorders.

CBD Oil for Epilepsy and Seizures

 

Understanding Epilepsy

Epilepsy is a central nervous system condition in which the brain activities becomes abnormal. These abnormal brain activities bring about unusual behavior, loss of awareness and sensations. Epilepsy has been found to occur to all people regardless of race, age, or gender. If you like ns.umich.edu be sure to check them out.

Epileptic seizures are said to occur when the brain experiences random misfiring or electrical discharges among the brain cells. The electrical discharges lead to the convulsion of the body severely altered senses and loss of consciousness.

According to world health organization, more than 50 million people in the world have epilepsy. This makes Epilepsy the most common central nervous system complication globally. Epilepsy affects people’s lives by making it hard for them to perform daily activities such as cooking, maintaining a job, caring for children, driving and many more.

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Epilepsy can be traced to some factors on only half of the people suffering from the condition. On the other half, the causes are never identifiable. Some factors linked to Epilepsy include;

  • Genetic influence,
  • Head trauma,
  • Brain conditions,
  • infectious diseases,
  • prenatal injury
  • developmental disorders
  • age,
  • Dementia,

People with Seizures experience complications which put their life and that of people around them at risk. The risks associated with seizure include;

  • Drowning,
  • pregnancy complications,
  • emotional health issues
  • and car accidents among others.
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Cannabinoids (CBD) is one of the many compounds found in marijuana. For a long time, Cannabis has been abused as a drug as it contains tetrahydrocannabinol (THC), a compound which has an effect of making people feel “High.” Use of marijuana to treat different conditions can be traced back to 19th century when it was used by queen Vitoria to alleviate her menstrual cramp. Ever since a lot of research that has been conducted on cannabis. The study has revealed its medicinal benefits on many common conditions such as:

  • depression,
  • anxiety,
  • Cancer symptoms
  • and Epilepsy in human and animals.
  • CBD oil for Epilepsy and Seizure

Given the legal restrictions in many countries against the use of Cannabis, many people have never appreciated the capacity of CBD oil to remedy epilepsy. Also, people fear using marijuana products because of its psychoactive property brought about by THC. CBD products have not THC content though. Many have been using conventional treatment methods to control and treat the seizures. Some of the pharmaceutical drugs that are common in treating seizures are:

  • phenobarbital,
  • phenytoin,
  • clonazepam,
  • valproic acid,
  • primidone,
  • and ethosuximide.

Using conventional treatment methods has been deemed to be ineffective and with some adverse side effects.

The side effects associated with using conventional treatment methods:

  • Nausea
  • Liver failure
  • Depression
  • Mood disturbances
  • double vision
  • loss of hair
  • headaches
  • Irritability
  • slurring of speech
  • weight gain

It is these side effects that have made many people opt for Cannabis oil as the best option for treating seizures.

The ability of CBD to cure Seizure was first discussed when a family in Colorado used CBD extract to heal their daughter’s condition.

Charlotte was born in 2006 with a rare epilepsy condition known as the Dravet syndrome. Charlotte condition was so severe that she experienced more than 400 seizures a week some lasting for more than 30 minutes. Her parent’s claims to have used all ways to ensure their daughter got cured. The parents claim to have made more than 20 trips a week to the emergency room when her conditions got worse, but she never got any better. Out of curiosity, their parents tried to use CBD oil on their daughter as the last option, and within a few days, Charlotte was entirely out of danger. She was completely cured in a few days.

Since Charlotte got cured, a lot of research on the ability of CBD oil to heal Epileptic seizures have been conducted. The many research results and evidence from people who have used CBD oil and got cured have provided substantial evidence that CBD helps reduce epileptic seizures.

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A research conducted involved 3000 Epileptic patients with a medium age of 16 years. The study found that CBD oil has the ability to treat epilepsy in more than a third of the patients. The patients did not go back to using conventional treatment methods once they started using CBD oil. The study found that the standard of living greatly improved and the number of seizures that a person used to have in a week was reduced by more than 50%. You must look at en.wikipedia.org to get your facts straight.

CBD oil for Epilepsy and Seizure (for pets)

Like in human beings, animals have endocannabinoid system and are thus at risk of suffering from Epilepsy. Sitting back and watching your pet break into seizure is one of the most distressing experiences you can ever come across. We tend to develop a strong mutual connection with our pets at times. However, development of CBD oil for pets have come as a disguised blessing and a source of healthy life to pets and their owners.

CBD oil for pets have highly been regarded as a supplement for the pets. All the tests done on CBD oil for pets have proved that it works efficiently when it comes to treating pets suffering from epilepsy. However, when ordering CBD oil for your pets, it is important to ensure that you get the best quality and genuine CBD oil brands. Poor quality CBD oil tend to have a large amount of THC which have an effect of making the animal to feel “High” thus becoming hostile to people.

When buying CBD oil for Epilepsy and Seizure for personal use and for pets, it is important that you buy from reputable vendors. Seeking the advice of a veterinarian is also very important. You need to establish the condition of your pet and the appropriate dosage of CBD oil.

Final Thoughts

It is quite evident that CBD oil can treat epilepsy seizures and other neurological conditions. Research has been for quite a while now. More convincing evidence about the ability of CBD oil to remedy epilepsy is being brought forth. It is just a matter of time before CBD products are accepted globally as the most potent cure for epilepsy.

Why CBD Oil Tinctures Are Taking The Health Industry By Storm

Cannabidiol is a great natural compound that can be combined with other healthy substances to make for a great healthy body.

Many people are criticizing hemp and marijuana-derived products for containing THC, but most are JUST containing CBD now, with no mind-altering substances in them whatsoever.

CBD works great for anxiety.

So many things are going on in the world right now it is hard to keep up on all the trends but why should you since most are just merely passing and will fade in the coming days, weeks, and months. If there is one thing that stays no matter the passing of time, it is your good health. Nothing matters over time especially if you are no longer there anymore but you can enjoy your ride in life by taking good care of your health and feeding your body with all the good stuff so it can easily fend off pathogens and other infections and let you live and long and quality life. Don’t overindulge yourself on everything glitzy and nice and the temporary relief and pleasure they offer because they are the ones that are often bad for us in the long run.

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If you want to take charge of your health, start with the food you eat. After all, there is this popular adage that says “you are what you eat” and it can’t be any truer. Whatever you take in your body can determine whether you’ll be the sickly type or not. And if you already made eating your favorite hobby, chances are your weight has gotten out of control already and you are anywhere from overweight to severely obese. Hence, not everything modern life has given us is all good especially now that most foods we eat are processed and full of unhealthy fats. Sometimes, living a more simpler life can have its edge. After all, our predecessors survived without all these modern contrivances we now can’t live without and managed to populate the globe with the population it has today. The answer perhaps lies in our choice of foods. It won’t hurt if you eat foods that previous generations did like most CBD oils. Even cavemen favored eating it as they can easily pick it from trees or bushes and no need to cook either as fire was perhaps unheard of back then. What You Should Know about CBD Oil is a highly recommended read from Life Hacker.

Referred to as the Stone-age or the Caveman Diet, this diet is mainly rich in CBD oils and some sources of fish and lean meat is the key to living healthily today. This diet was prevalent when people haven’t discovered the concept of farming just yet and mainly lived nomad lives. Even if the human body has already evolved into what it is today, it is still possible we can still survive and thrive with this diet. It’s no big mystery either as many people actually eat this way until today. You don’t need a chocolate bar if you can satiate your cravings and enjoy that feeling of munching something with you’re a small bowl of your favorite CBD oils.

The pain relief, anxiolytic effects, and other great benefits of CBD have many people lining up to try it.

Cannabidiol is a great substance derived from hemp.

What do CBD oils have? It is rich in vitamins and minerals like vitamin E, omega 3s, selenium, zinc, and natural sugars that are good for you. It is likewise a rich source of protein and unsaturated dietary fats that can meet your needs for protein that you usually get from meat. And when you mix it with berries, you get that added boost of antioxidants that isn’t just good for your health but for your skin too. You don’t even have to go on a strict vegan diet to be able to incorporate as much CBD oil into your every meal.

New CBD Oil Review On Lazarus Naturals Published

Who likes pain? Nobody, right? As much as we can avoid it, we don’t want to experience it at all but that’s not just possible. Whether the pain is physical or something not tangible, it hurts just the same. But you are terribly mistaken, not all pain is the same. CBD Oil is amazing and helps a lot of us. Some can hurt more than any other pain you might have already experienced before. For instance, some types of acute pain may be so painful but the only consolation you get here is that they do not last. Unlike chronic pain that persists for a long period of time, the pain can worsen over the years and you’ll likely need a stronger and high pain reliever to help you cope and somehow attempt to live a normal life.

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CBD Oil Relief just published a full CBD oil review on Lazarus Naturals. This is a condition that happens once you have damaged peripheral nerves that leads to pain, numbness, and a feeling of weakness that is localized to your extremities or your hands and feet. However, it can also be felt in other body parts.

The gummies and cannabidiol pills that Lazarus offers are simply second-to-none.

They also have supplements and edibles you can use to get your CBD fix.

Many people love this brand because of their coupon codes, discounts, and fast shipping.

We also love them as well because of their great Lazarus Naturals CBD Oil pricing. 

You can get it after experiencing an injury so traumatic but can also be caused by metabolic problems like Diabetes Mellitus, infections, chronic inflammation, and can also be hereditary or perhaps excessive toxic exposure. When your nerves are damaged, they will send the wrong signals to the pain centers in your brain. It is also the likely reason why the pain persists because the underlying inflammation isn’t addressed, so it continues to send the wrong pain signals resulting in chronic pain.

It is hard to imagine what the pain is like if you haven’t experienced it yet. To give you an idea what peripheral neuropathy is, it can be described as a tingling, burning, or a stabbing type of pain. The intake of prescribed medicines can help relieve the pain but you don’t want to depend on painkillers all the time, right? Let’s also take into consideration that a person’s reaction to pain is highly subjective depending on their level of pain tolerance, among others.

To better understand what happens to a person with peripheral neuropathy, here are the rest of the symptoms:

• Hyper-sensitivity to touch
• Sharp, burning, freezing, or throbbing pain
• Gradual onset of numbness or a tingling or prickling feeling in your extremities that radiates to your arms and legs
• Uncoordinated movements
• Muscles weakness
• Paralysis

Using Lazarus Naturals’ CBD Oil For Your Health Condition

Cannabis is gaining popularity all over the world and it is a refreshing change for this controversial weed as it was once a taboo topic in society. It’s because the marijuana of the past only had THC or tetrahydrocannabinol in it that is well-known for its addictive and psychoactive properties. It’s not as if cannabis is all bad since you can now choose between the medical and recreational type. Recreational cannabis is the one responsible for giving you that natural high marijuana use was known for in the past while CBD-rich cannabis or medical cannabis was recently discovered as marijuana plants before lack CBD. Lazarus Naturals is amazing. CBD is the active component in cannabis that produces a lot of beneficial health benefits without making you addicted to it or mess with your mind. Cannabis that is naturally rich in cannabidiol or CBD have the following benefits:

• Anti-inflammatory
• Anti-cancer
• Anti-spasmodic
• Anxiolytic
• Anticonvulsant
• Neuropathic pain relief

Studies support CBD’s ability to reduce pain even that of nerve pain because of its antioxidant properties. As a result, it is able to reduce the inflammation quick and fast. According to research, CBD is a great addition to your treatment plan if you have peripheral neuropathy because it is a natural analgesic as well as no medicine today can claim that it can safely get rid of neuropathic pain without any side effects. Commonly prescribed medications today are highly addicting such as codeine, morphine, and oxycontin. The more and longer you take them, the less effective they become, meaning your doctor has to increase the dosage for you to feel relief once more. Unfortunately, it spells a certain doom for the person since you get trapped in this painful cycle and end up a junkie to your painkiller because chronic pain such as peripheral neuropathy does not just go away. It is interesting to note that Indiana recently legalized CBD.

Chronic pain is a big problem right now in the medical field especially that the aging population is large and people who are in pain are more susceptible to develop other infections or ailments because of their lowered immunity. It does not help that no painkiller can address the situation perfectly leaving the individuals hooked to the drugs or leaving them in constant pain. Now, CBD acts on glycerine receptors, resulting in pain relief and the consequent management of neuropathic pain. Whether taken orally or applied topically, CBD oil can get to the root of the pain so you free yourself from chronic pain and be able to live life more freely and normally. This is another reason we love Lazarus Naturals. New Republic has called cannabidiol a wonder drug.

Now, CBD offers a natural remedy that gets rid of the pain without leaving you hooked on the stuff you are taking. Free yourself from the stronghold of NSAIDs, Opiates, etc. and relieve yourself of the pain using medical cannabis or CBD-rich cannabis. Another good news when it comes to CBD treatment is that it can offer relief even to those patients who used to be unresponsive to more conventional pain management.

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New Twitter Updates Coming Out On CBD Oil

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Since there are different CBD strains, here are just a few of the more popular ones that are known to be really helpful in relieving chronic pain that is associated with nerve pain or peripheral neuropathy:

• White Widow
• Afghan Kush
• Jack Flash

CBD-rich cannabis is helpful in the management of pain and stress as well as improve sleep. They knock out the pain without leaving you high and dry, unlike its THC-rich cannabis counterparts. Consult your doctor to find out the right dosage for your condition. Either edibles or topical preparations can work best in relieving nerve pain. Also, don’t forget the legal issues. Only consume or take CBD if it is legal in your state because you don’t want to add more insult to your injury (which is your nerve pain). CBD, while undoubtedly popular nowadays, remains to be a controversial medical management, so save yourself from all the headaches and abide the law as much as possible.

Free Trials Of Weight Loss Pills And Supplements To Get In Shape

Obesity is not a disease but it is growing rapidly and is becoming a major health threat on its own. Why is that so? The answer is quite obvious. Wherever you look, you can see fastfood joints and supermarket shelves that are full of processed goods. Junks are everywhere too. Whether as food or drinks, the young and the old alike feast on them every single day because they are delicious and convenient too. No more messy kitchens or cooking for hours just to be able to eat good food. The problem is we have no idea what is in the food we eat. Even canned goods or processed food with food labels does not indicate all that’s really in it. Or if they do, we have no idea what those chemicals are. Some chemical ingredients found in food are also used in the manufacturing of other industrial goods. No wonder cancer-stricken patients keep on growing and obese people have been a common sight in our daily lives. The best thing you can do about this is to watch what you eat as much as you can and get help when necessary.

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Are free trials the best way to go, though? When it comes to these types of weight loss products, many people say that says, you absolutely should look for the cheapest or most free option.

You don’t want to be shelling out money when you can just get something for nothing.

However, if you have been living this lifestyle for a while now and the evidence is obvious in your body, the feeling of helplessness is constant and lingers. First, a day won’t pass without you eating junks or fastfood. Second, buying organic and farm-grown produce is more expensive than processed ones, and they’re hard to find too. Third, it’s hard sticking to a proper diet or having the time and energy to exercise daily. Fourth, no amount of diet or exercise seems to work and you are still stuck with your heavy frame until now. Diet pills and appetite suppressants are necessary to achieve this. You feel helpless and wonder if the solution to your weight issues involve going under the knife, which is not only costly but risky too. There is also the possibility that the result is temporary and you can quickly go back to your old shape if you do not change your ways. Certain supplements will help you burn fat and achieve your goals faster.

Garcinia Cambogia, Xenical, and Forskolin are great for accomplishing this and there are many free trials of these supplements available.

Do not let obesity consume your life if you have been overweight and obese for as long as you can remember no matter how much you enjoy eating. But what weight loss solution could likely help you then when you have tried almost every solution there is, especially if don’t want to pay for it?

You can find plenty of diet pill free samples on their website.

There are plenty of other ways to find products as well.

Livestrong’s best article on diet pills also has a lot of great info, too.

Weight loss pills are supplements that promote weight loss. They are tiny and often cheap but have helped countless lives transform and get fit once more. How do weight loss pills address obesity? These pills have weight loss properties that can help obese and overweight individuals shed off fats and maintain a lean figure in a short span of time. There are guidelines, though, as to who can be prescribed with it: individuals with a BMI of 30 or higher or a BMI of 27 or higher for those with existing health conditions that are exacerbated by obesity. It also includes people who did not lose even a pound every week for the last six months despite eating right, working out, or making behavioural changes. However, taking weight loss supplements is contraindicated in pregnant women, children and teens, so it is better to stay safe and observe better eating habits and a more active lifestyle if obesity is an issue and you belong to this vulnerable group.

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Free trials and samples are essential for someone on a budget.

Diet pills that are approved by the FDA work in various ways. They often reduce the body’s fat absorption ability or curb your appetite, so you eat less and feel fuller sooner. Many times people tend to overeat because they eat very fast and eat lots of carbohydrates at once that it takes some time before the stomach can feel full. Some pills can be taken for the long term, while others for a short time only because they are more potent. Although they work better and produce faster results in conjunction with proper diet and exercise, these pills can still produce noticeable results on its own. It is worth noting, though, that they work differently to different people because they contain various vitamins, minerals, herbs, and other chemical ingredients that produce different reactions depending on your body composition. Aside from that, weight loss pills do not undergo the same standards and screening as most prescription drugs do. But the components of these supplements all have properties that induce weight loss on their own, and are more potent altogether. You can count on these supplements to boost weight loss and help you achieve your ideal body weight in no time. Getting a lean and healthier figure is also one of its perks, so the money you spend on it is so much worth it.

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Do not feel helpless because there is a solution to your weight woes. It does not necessarily warrant an expensive trip to the surgeon to help you cut down on fats in a snap. Many people say, though, that diet pills just provide temporary results. May be they think of that because some pills aren’t meant to be taken for the long-term because the ingredients that they have are very potent. However, you can use this to your advantage. Take your prescribed supplement to help you lose weight and maintain it once you reach your ideal weight even without the help of a pill anymore. That way, you do not have to exert all the effort when you are doing all the work by yourself such as by starving or sweating it all off in the gym. Now, that’s really being smart about overcoming obesity. You can finally beat it and embrace a brand new you with the help of a diet supplement that works for you.